FBI Special Agent Sean Archer is trying to find a biological weapon that has been placed in Los Angeles by the sadistic terrorist-for-hire and criminal mastermind Castor Troy. Archer has been hunting Troy for the last 8 years and is consumed by revenge because Troy is responsible for the death of Archer's son. To do this, Archer must 'borrow' Troy's face using a surgical procedure to go undercover as Troy, but things go wrong when Troy assumes the identity of Archer.
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